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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
10.61
Human Site:
S199
Identified Species:
14.58
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S199
V
S
L
K
V
S
E
S
V
I
D
V
K
T
T
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S199
V
S
L
K
V
S
E
S
V
I
D
V
K
T
T
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
V199
S
L
K
V
S
E
S
V
I
D
A
K
T
T
M
Dog
Lupus familis
XP_533766
1089
122761
S199
V
R
L
K
V
S
E
S
V
I
N
V
K
T
T
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
N199
K
A
S
E
N
V
V
N
V
N
T
S
E
D
V
Rat
Rattus norvegicus
NP_446123
1093
121882
V199
A
K
A
S
E
S
V
V
K
V
N
T
A
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
T199
D
I
K
V
S
S
L
T
L
E
V
P
E
G
V
Chicken
Gallus gallus
O42184
1433
161009
S203
S
G
S
V
S
N
L
S
E
A
G
S
L
K
K
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
Q199
E
Q
E
S
I
E
D
Q
T
E
S
D
G
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
P151
P
D
T
E
P
S
L
P
D
S
I
V
I
I
A
Honey Bee
Apis mellifera
XP_394037
1326
150590
E226
E
D
V
K
M
R
S
E
D
K
E
T
R
E
Y
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
V781
K
V
F
F
K
A
G
V
L
A
H
L
E
D
I
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
K199
K
A
D
N
K
E
V
K
S
E
A
V
L
Q
P
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
V194
E
A
S
R
V
D
E
V
E
A
P
S
I
L
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
L175
S
S
G
Y
K
T
S
L
Q
P
N
E
K
L
E
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
6.6
86.6
N.A.
6.6
6.6
N.A.
6.6
6.6
0
0
N.A.
13.3
6.6
0
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
33.3
20
N.A.
26.6
13.3
0
13.3
N.A.
20
33.3
26.6
13.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
18
6
0
0
6
0
0
0
18
12
0
6
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
6
0
0
6
6
0
12
6
12
6
0
12
6
% D
% Glu:
18
0
6
12
6
18
24
6
12
18
6
6
18
12
6
% E
% Phe:
0
0
6
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
6
0
0
0
6
0
0
0
6
0
6
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
6
% H
% Ile:
0
6
0
0
6
0
0
0
6
18
6
0
12
6
6
% I
% Lys:
18
6
12
24
18
0
0
6
6
6
0
6
24
6
6
% K
% Leu:
0
6
18
0
0
0
18
6
12
0
0
6
12
18
0
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
6
6
6
0
6
0
6
18
0
0
0
0
% N
% Pro:
6
0
0
0
6
0
0
6
0
6
6
6
0
0
6
% P
% Gln:
0
6
0
0
0
0
0
6
6
0
0
0
0
6
0
% Q
% Arg:
0
6
0
6
0
6
0
0
0
0
0
0
6
0
0
% R
% Ser:
18
18
18
12
18
36
18
24
6
6
6
18
0
0
0
% S
% Thr:
0
0
6
0
0
6
0
6
6
0
6
12
6
24
18
% T
% Val:
18
6
6
18
24
6
18
24
24
6
6
30
0
0
18
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _